how is pyruvate formed, check these out | How is pyruvate formed in glycolysis?
Pyruvate is produced by glycolysis in the cytoplasm, but pyruvate oxidation takes place in the mitochondrial matrix (in eukaryotes). So, before the chemical reactions can begin, pyruvate must enter the mitochondrion, crossing its inner membrane and arriving at the matrix.
How is pyruvate formed in glycolysis? In a series of steps that produce one NADH and two ATP, a glyceraldehyde-3-phosphate molecule is converted into a pyruvate molecule. This happens twice for each molecule of glucose since glucose is split into two three-carbon molecules, both of which will go through the final steps of the pathway.
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